N-Acetyl-L-glutamic acid

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Reputable factory supply N-Acetyl-L-glutamic acid 1188-37-0 in stock with high standard

  • Molecular Formula: C7H11NO5
  • Molecular Weight: 189.168
  • Appearance/Colour: white crystalline powder 
  • Vapor Pressure: 3.48E-11mmHg at 25°C 
  • Melting Point: 194-196 ºC (lit.) 
  • Refractive Index: -15 ° (C=1, H2O) 
  • Boiling Point: 495.9 ºC at 760 mmHg 
  • PKA: 3.45±0.10(Predicted) 
  • Flash Point: 253.7 ºC 
  • PSA: 103.70000 
  • Density: 1.354 g/cm3 
  • LogP: -0.16860 

N-Acetyl-L-glutamic acid(Cas 1188-37-0) Usage

Purification Methods

A likely impurity is glutamic acid. Crystallise it from boiling water. It inhibits N-acetyl-L-glutamate synthase. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1948 1961, Shigesada & Tatibana Eur J Biochem 84 285 1978, Coude Biochem Biophys Res Commun 102 1016 1981, Beilstein 4 IV 3047.]

InChI:InChI=1/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10)11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13)/p-2/t5-/m0/s1

1188-37-0 Relevant articles

Deciphering Carbamoylpolyoxamic Acid Biosynthesis Reveals Unusual Acetylation Cycle Associated with Tandem Reduction and Sequential Hydroxylation

Qi, Jianzhao,Wan, Dan,Ma, Hongmin,Liu, Yuanzhen,Gong, Rong,Qu, Xudong,Sun, Yuhui,Deng, Zixin,Chen, Wenqing

, p. 935 - 945 (2016)

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New method of synthesis of D,L-5-oxoproline

Ermakova, G. A.,Skachilovw, S. Ya.,Yurchenko, N. I.

, p. 33 - 34 (1995)

A new method for synthesis of D,L-5-oxop...

Oxidative Damage in Aliphatic Amino Acids and Di- and Tripeptides by the Environmental Free Radical Oxidant NO3?: the Role of the Amide Bond Revealed by Kinetic and Computational Studies

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Kinetic and computational data reveal a ...

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1188-37-0 Process route

Ketene
463-51-4

Ketene

L-glutamic acid
56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6

L-glutamic acid

1-methyl-4-nitrosobenzene
623-11-0

1-methyl-4-nitrosobenzene

Acetyl-D,L-glutaminsaeure
5817-08-3

Acetyl-D,L-glutaminsaeure

N-acetyl-(S)-glutamic acid
1188-37-0

N-acetyl-(S)-glutamic acid

Conditions
Conditions Yield
L-glutamic acid
56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6

L-glutamic acid

acetic anhydride
108-24-7

acetic anhydride

N-acetyl-(S)-glutamic acid
1188-37-0

N-acetyl-(S)-glutamic acid

Conditions
Conditions Yield
In water; for 0.0666667h; Irradiation;
98%
at 0 - 20 ℃;
61%
With water;
58%
With acetic acid; Heating;

1188-37-0 Upstream products

  • 463-51-4
    463-51-4

    Ketene

  • 56-86-0
    56-86-0

    L-glutamic acid

  • 623-11-0
    623-11-0

    1-methyl-4-nitrosobenzene

  • 108-24-7
    108-24-7

    acetic anhydride

1188-37-0 Downstream products

  • 2361-99-1
    2361-99-1

    N -Acetyl-L-glutaminsaeure-dimethylester

  • 5817-10-7
    5817-10-7

    N 2 -acetyl-N 5 -phenyl-DL-glutamine

  • 149-87-1
    149-87-1

    Pyroglutamic acid

  • 1446-19-1
    1446-19-1

    diethyl N-acetyl L-glutamic ester

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